# The heart to heart a rest-vascular diseases # **Tags:** * Loaded with inheritance to cardiovascular disease * The health of hypertension * In a group of drugs for high blood pressure :::warning Diuretiko (Diuretika) ay nagpapataas ng pag-ihi ng katawan, na nagreresulta sa pagbaba ng presyon ng dugo. Simpleng paliwanag: Ang tuloy-tuloy na pag-ihi ng katawan ay nagdudulot ng pagbaba ng dami ng plasma sa dugo at sa gayon ay mas kaunting likido sa mga ugat — bumababa ang presyon sa mga pader ng ugat. ::: [](https://cardio-balance-ph.store-best.net) <div style="height:500px;"></div> ## Loaded with inheritance to cardiovascular disease ## <div class="alert alert-info" role="alert"> Leaves of the Banaba tree, also known as Crape Myrtle, offer multiple medicinal properties. Scientific studies and research found that it can lower triglyceride levels by 35% and increases good cholesterol level (HDL) by 14%. 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Here is a scientific Text is in German on the topic of a group of drugs for high blood pressure: Antihypertensive drugs: A Summary of important drug groups High blood pressure, known medically as hypertension, is a worldwide health problem and is considered an important risk factor for cardiovascular diseases such as heart attack, stroke and kidney failure. The pharmacotherapy of hypertension includes several groups of active substances, the use of different physiological mechanisms to reduce blood pressure. 1. ACE inhibitors (Angiotensin‑converting enzyme inhibitor) ACE inhibitors such as Enalapril or Ramipril under the enzyme for the conversion of Angiotensin I to the vasoconstrictor substance Angiotensin II is responsible press. The reduction of Angiotensin II leads to a dilation of the blood vessels and a reduction in peripheral vascular resistance. In addition, ACE inhibitors decrease Aldosterone secretion, resulting in a reduced water and sodium recovery in the kidney. 2. AT1‑receptor blockers (Sartans) This group, including Losartan and Valsartan, selectively blocks the AT1 receptors for Angiotensin II, Thereby preventing vasoconstrictor and aldosterone-stimulating effects. Sartans are considered to be well tolerated and are often used as an Alternative to ACE‑inhibitors in patients with an incompatible cough. 3. Calcium antagonists Calcium antagonists such as amlodipine or nifedipine to inhibit the influx of calcium ions (Ca 2+ ) in the smooth muscles of the blood vessels. This leads to Relaxation of the vascular wall, and thus to a reduction in blood pressure. They are especially recommended for use in elderly patients and in isolated systolic hypertension. 4. Beta-blockers Agents such as Metoprolol and Bisoprolol act through the Blockade of β‑adrenergic receptors. Decrease the heart rate and cardiac output, which leads to a reduction in Cardiac output and in blood pressure. Beta-blockers play a special role in patients with concomitant coronary artery disease or congestive heart failure. 5. Diuretics Thiazide diuretics (e.g. hydrochlorothiazide) and loop diuretics (e.g., furosemide), promote the excretion of water and salt through the kidneys. As a result, the blood volume and thus blood pressure is reduced. Diuretics are often used in combination therapies, and particularly in the elderly and in African-American patients effectively. 6. Combination therapy Due to the multifactorial pathophysiology of hypertension monotherapy is often not sufficient. Combinations of two or more active agents (e.g., ACE inhibitor + calcium antagonist or Sartan + diuretic) allow for a more effective blood pressure control with less substance dosage and thus reduce the rate of side effects. Conclusion Dieusgehend of the individual patient characteristics (age, comorbidities, ethnicity, side-effects) should be taken in the choice of anti-hypertensive drugs individually. An evidence-based, to the pathophysiology of customized pharmacotherapy a significant reduction of cardiovascular complications, and improves quality of life and expectation of the parties Concerned. Would you like me to make a certain section in more detail or other medication groups to add?